fungicidal composition and method for controlling plant diseases

专利摘要:
patent abstract: "fungicidal composition and method for controlling plant diseases". The present invention relates to a fungicidal composition useful as an agricultural and horticultural fungicide having markedly improved control effects against plant diseases, and to a method for controlling plant diseases using the composition. a fungicidal composition comprising, as active ingredients, (a) 3- (2,3,4-trimethoxy-6-methylbenzoyl) -5-chloro-2-methoxy-4-methylpyridine or its salt and (b) at least one fungicide selected from the group consisting of bixafene, fluxapiroxade, penflufen, isopyrazam, fluopyram, ametoctradine, fenpyrazamine and sedaxane, and a method for controlling plant diseases comprising applying the fungicidal composition to plants.
公开号:BR112014000391B1
申请号:R112014000391
申请日:2012-06-15
公开日:2019-08-27
发明作者:Ogawa Munekazu；Kawai Yusuka
申请人:Ishihara Sangyo Kaisha；
IPC主号:

专利说明:

description
Technical Field [001] The present invention relates to a composition useful as an agricultural and horticultural fungicide having notably improved control effects against plant diseases, and to a method for controlling plant diseases using such a composition.
Prior Art [002] Patent Document 1 describes that a benzoylpyridine derivative which is an active ingredient of the fungicidal composition in the present invention is useful as a fungicide and can be mixed with or used in combination with another fungicide as the case requires. In addition, Patent Documents 2 and 3 describe that by using the benzoylpyridine derivative in combination with another specific fungicide, it is possible to obtain a fungicidal composition having excellent synergistic effects. In addition, Patent Document 4 describes a composition comprising the benzoylpyridine derivative and isopyrazam, and Patent Document 5 also describes a composition comprising the benzoylpyridine derivative and fluxpyroxade, bixafen, fluopyram, isopyrazam, silkxane, silkflane, etc.
[003] However, it has not been specifically known that the fungicidal composition in the present invention has remarkably excellent fungicidal effects.
Prior Art Documents
Patent Document
Patent Document 1: W002 / 02527
Patent Document 2: W02005 / 041663 Patent Document 3: WO2010 / 002026
Petition 870180062559, of 07/20/2018, p. 6/32
2/19
Patent Document 4: W02007 / 115766 Patent Document 5: WO2012 / 016989
Description of the Invention
Technical Problem [004] Each of the active ingredients of the fungicidal composition in the present invention, may be inadequate in its control effect against a disease of a specific plant, or its residual effect may last only a relatively short time, and therefore, depending on of the condition for application, it can practically only have an inadequate control effect against plant diseases.
Solution to the Problem [005] The present inventors conducted research to solve the above problems and as a result, found that when (a) 3- (2,3,4-trimethoxy-6-methylbenzoyl) -5-chloro-2- methoxy-4-methylpyridine or its salts and (b) at least one fungicide selected from the group consisting of bixafen, fluxpyroxade, penflufen, isopyrazam, fluopyram, ametoctradine, phenpyrazamine and silkxane are used in combination, an unexpected excellent fungicidal effect can be obtained when compared with a case in which the respective compounds are used alone, and have accomplished the present invention.
That is, the present invention provides a fungicidal composition comprising, as active ingredients, (a) 3- (2,3,4-trimethoxy-6methylbenzoyl) -5-chloro-2-methoxy-4-methylpyridine or its salts (hereinafter sometimes referred to simply as a component (a)) and (b) at least one fungicide selected from the group consisting of bixafen, fluxpyroxade, penflufen, isopyrazam, fluopyram, ametoctradine, phenpyrazamine and silkxane (hereinafter sometimes referred to simply as a component (b)). In addition, the present invention provides a method for controlling plant diseases, which comprises applying the above fungicidal composition to plants.
Petition 870180062559, of 07/20/2018, p. 7/32
3/19
Advantageous Effects of the Invention [007] The fungicidal composition of the present invention has a synergistic effect, that is, a fungicidal effect higher than the mere addition of the respective fungicidal effects of the active ingredients, against plant diseases. More specifically, even if components (a) and (b) being active ingredients of the fungicidal composition of the present invention show only an inadequate control effect against specific plant diseases when they are used alone, respectively, using them in combination, they show synergistic control effect against plant diseases and thus exhibit an almost sufficient control effect.
Description of Modalities [008] 3- (2,3,4-T ri methoxy-6-methyl I benzoyl I) -5-chloro-2-methoxy-4 methylpyridine as the component (a) in the present invention can be obtained by a production process as described in Patent Documents 1 and 2 above. In addition, this is a compound known by the common name pyrophenone.
[009] Component (a) can be a salt. The salt can be any agriculturally acceptable salt, and it can, for example, be an inorganic acid salt such as a hydrochloride, a perchlorate, a sulfate or a nitrate; or an organic acid salt such as an acetate, fumarate or methanesulfonate.
[0010] Each of bixafeno, fluxapyroxad, penflufeno, isopirazam, fluopiram, ametoctradina, fenpirazamina and sedaxano as component (b) in the present invention is a compound disclosed as a fungicide in The Pesticide Manual (Manual of Pesticides) (15th edition , British Crop Protection Council) or SHIBUYA INDEX 15th edition (SHIBUYA INDEX RESEARCH GROUP).
[0011] Among them, bixafen, fluxpyroxade, penflufen, isopyrazam,
Petition 870180062559, of 07/20/2018, p. 8/32
4/19 Silkxane and fluopyram are composite II electron carrying inhibitors having a carboxamide structure. More specifically, bixafen, fluxpyroxade, penflufen, isopyrazam and silkxane are electron carrying composite II inhibitors classified in pyrazole carboxamide compounds, and fluopyram is an electron carrying composite II inhibitor classified in pyridinyl-ethylbenzamide compounds. [0012] Among the components (b) in the present invention, bixafen, fluxpyroxade, penflufen, fluopyram, ametoctradine and phenpyrazamine, which exhibit higher synergistic effects when used in combination with component (a), are preferred, and bixafen and fluopyram are preferred. most preferred.
[0013] The fungicidal composition of the present invention is particularly useful as an agricultural and horticultural fungicide. As an agricultural and horticultural fungicide, it is effective in controlling diseases such as porous downy mildew, crust, rust, snow mold, snow pest, loose rust, cercosporiosis, leaf spot or cereal glaze stain (Hordeum vulqare, Tricum aestivum , etc.); melanosis or citrus crust (Citrus spp., etc.); flowering pest, porous mildew, alternaria leaf spot, crust, anthracnose, stain, ring rot, fly droppings, sooty blotch or apple fruit spot (Malus pumila); crust, black spot, porous mildew or Phytophthora pear rot (Pyrus Pirifolia, var. culta); ring rot or porous downy of European pear (Pyrus communis); brown rot, crust or Phomopsis rot from peach rot (Prunus Persica, etc.); anthracnose, ripe rot, porous downy mildew, cucurbit mildew, gray mold, Isariopsis leaf spot or swelling of grape branch (Vitis vinifera spp., etc.); anthracnose, leaf spot, porous downy mildew or Japanese persimmon fly droppings (kaki persimmons, etc.); anthracnose, porous downy mildew, gummy rot, cucurbit mildew, Phytophthora rot or Cercospora leaf spot
Petition 870180062559, of 07/20/2018, p. 9/32
5/19 cucurbit (Cucumis melo, etc.); early rot, leaf mold, delayed rot, gray mold or porous mildew of tomato (Lycopersicon esculentum); Alternaria leaf spot of cruciferous vegetables (Brassica sp., Raphanus sp., etc.); early rot or delayed potato rot (Solanum tuberosum); porous downy mildew, gray mold or strawberry anthracnose (Fraqaria, etc.); and gray mold or porous downy mildew from various cultures. It is particularly effective against diseases of cereal plants, fruits (particularly apple, pear and European pear) and vegetables (particularly cucurbits and tomatoes). In addition, it is also effective for controlling soil diseases caused by plant pathogens such as Fusarium, Pythium, Rhizoctonia, Verticillium and Plasmodiophora.
[0014] The components (a) and (b) that make up the fungicidal composition of the present invention are, in the same way as conventional agricultural chemicals, mixed with various adjuvants and formulated in various formulations such as powder, granules, granules dispersible in water , a wettable powder, a water-based suspension concentrate, oil-based suspension concentrate, water-soluble granules, an emulsifiable concentrate, a soluble concentrate, a paste, an aerosol and an ultra-low volume formulation. However, as long as the purpose of the present invention can be realized, any type of formulation that is commonly used in this field is applicable. Such adjuvants include solid vehicles such as diatomaceous earth, slaked lime, calcium carbonate, talc, white carbon, kaolin, bentonite, a mixture of kaolinite and sericite, clay, sodium carbonate, sodium bicarbonate, mirabilite, zeolite and amide; solvents such as water, toluene, xylene, naphtha solvent, dioxane, acetone, isophorone, methyl isobutyl ketone, chlorobenzene, cyclohexane, dimethyl sulfoxide, dimethylformamide, dimethylacetamide, N-methyl-2-pyrrolidone and alcohol; anionic surfactants and disseminators such as a salt or acid
Petition 870180062559, of 07/20/2018, p. 10/32
6/19 of the fatty, a benzoate, an alkylsulfosuccinate, a dialkylsulfosuccinate, a polycarboxylate, an alkyl sulfuric acid salt, an alkyl sulfate, an alkylaryl sulfate, an alkyl diglycol ether sulfate, an ester alcohol salt sulfuric acid, an alkyl sulfonate, an alkylaryl sulfonate, an aryl sulfonate, a lignin sulfonate, an alkyldiphenyl disulfonate ether, a polystyrene sulfonate, an alkylphosphoric acid ester salt, an alkylaryl phosphate, a styrylyl phosphate , the alkyl polyoxyethylene ether sulfuric acid ester salt, a polyoxyethylene alkyl ether sulfuric acid sulfate, a polyoxyethylene alkyl ether sulfuric acid ester salt, a polyoxyethylene alkyl ether phosphate, a salt of polyoxyethylene alkyl ether polyoxyethylene alkylaryl phosphoric acid, and a salt of a naphthalene sulfonate condensate with formalin; non-ionic surfactants and disseminators such as a sorbitan fatty acid ester, a glycerin fatty acid ester, a fatty acid polyglyceride, a fatty acid alcohol polyglycol ether, acetylene glycol, acetylene alcohol, a block polymer oxyalkylene, a polyoxyethylene alkyl ether, a polyoxyethylene alkylaryl ether, a polyoxyethylene glycyl ether, a polyoxyethylene glycol alkyl ether, a polyoxyethylene fatty acid ester, a polyoxyethylene fatty acid ester, an ester of polyoxyethylene sorbitan polyoxyethylene glycerin fatty acid, a hydrogenated polyoxyethylene castor oil, and a polyoxypropylene fatty acid ester; and vegetable and mineral oils such as olive oil, kapok oil, castor oil, palm oil, camellia oil, coconut oil, sesame oil, corn oil, rice bran oil, peanut oil, oil cottonseed oil, soybean oil, rapeseed oil, linseed oil, tung oil (wood oil from China), and liquid paraffins. Such adjuvants can be selected from those known in the field since the purpose of the present invention can thus be accomplished. Still, several additives that are commonly usedPetition 870180062559, of 20/07/2018, p. 11/32
7/19 dosages, such as a filler, a thickening agent, an anti-settling agent, an antifreeze agent, a dispersion stabilizer, a phytotoxicity reducing agent, and an anti-mold agent, can also be employed . The mixing ratio of components (a) and (b) for the various adjuvants is usually 0.005: 99.995 to 95: 5, preferably 0.2: 99.8 to 90:10. In the current application of such a formulation, it can be applied as is, or it can be diluted to a predetermined concentration with a diluent such as water, and various spreaders can be added for this purpose, as the case requires.
[0015] Furthermore, the fungicidal composition of the present invention can be mixed with or used in combination with other agricultural chemicals such as a fungicide, an insecticide, an acaricide, a nematicide, a soil pesticide, an antivirus agent, an attractive, a herbicide and a plant growth regulating agent, thus more excellent effects can sometimes be obtained.
[0016] The compounds of active ingredients of a fungicide in the agricultural chemicals mentioned above and others, include, for example, (by common names, some of them are still in an application stage or testing codes of the Plant Protection Association of the Japan (Japan Plant Protection Association)):
[0017] anilinapyrimidine compounds such as mepanipyrim, pyrimethanil and cyprodinil;
[0018] triazolopyrimidine compounds such as 5-chloro-7- (4methylpiperidin-1-yl) -6- (2,4,6-trifluorophenyl) [1,2,4] triazole [1,5-a] pyrimidine; [0019] pyridinamine compounds such as fluazinam;
[0020] azole compounds such as triadimefone, bitertanol, triflumizole, etaconazole, propiconazole, penconazole, flusilazole, myclobutanil, cyproconazole, tebuconazole, hexaconazole, furconazol-cis, procloraz, mePetição 870180062559 12/32
8/19 tconazole, epoxiconazole, tetraconazole, oxpoconazole fumarate, protioconazole, triadimenol, flutriafol, diphenoconazole, fluquinconazole, fenbuconazole, bromuconazole, diniconazole, tricyclazole, probenazole, simeconazole, azefaconazole, pefurazol, pefurazol, trefazazol, pefurazole, pefurazole, trefazazole, pazazole, trefazazole;
[0021] quinoxaline compounds such as quinomethionate;
[0022] dithiocarbamate compounds such as maneb, zineb, mancozebe, polycarbamate, mety, propineb and take off;
[0023] organic chlorine compounds such as phthalide, chlorothalonil and quintozene;
[0024] imidazole compounds such as benomyl, thiophanate-methyl, carbendazim, thiabendazole, fuberiazole and cyazofamide;
[0025] cyanoacetamide compounds such as cymoxanil;
[0026] anilide compounds such as matalaxyl, metalaxyl-M (another name: mefenoxam), oxadixil, ofurace, benalaxyl, benalaxyl-M (another name: quiralaxyl, ciralaxil), furalaxil, ciprofuram, carboxine, oxycarboxine, tifluzamide, boscalide isothianyl and thiadinyl;
[0027] sulfamide compounds such as diclofluanide;
[0028] copper compounds such as cupric hydroxide and oxine copper;
[0029] isoxazole compounds such as himexazole;
[0030] organophosphorus compounds such as fosetyl-AI, tolclofosmethyl, S-benzyl O, O-diisopropylphosphorothioate, O-ethyl S, sdiphenylphosphorodithioate, aluminum ethyl hydrogen phosphonate, ediphenphos and iprobenfos;
[0031] phthalimide compounds such as captan, captafol and folpet; [0032] dicarboxyimide compounds such as procymidone, iprodione and vinclozoline;
Benzanilide compounds such as flutolanil, mepronil and benodanil;
Petition 870180062559, of 07/20/2018, p. 13/32
9/19 [0034] amide compounds such as pentiopyrad, furametpir, siltiofam, phenoxanil and fenfuram;
[0035] benzamide compounds such as zoxamide;
[0036] piperazine compounds such as triforin;
[0037] pyridine compounds such as pyrifenox;
[0038] carbinol compounds such as fenarimol and nuarimol;
[0039] piperidine compounds such as phenpropidine;
[0040] morpholine compounds such as phenpropymorph and tridemorph;
[0041] organotin compounds such as phentin hydroxide and fentin acetate;
[0042] urea compounds such as pencicurone;
[0043] cinnamic acid compounds such as dimetomorph and flumorfo;
[0044] phenyl carbamate compounds such as dietofencarb;
[0045] cyanopyrrole compounds such as fludioxonil and fenpiclonil;
[0046] strobilurin compounds such as azoxystrobin, cresoxim-methyl, metominostrobin, trifloxystrobin, picoxystrobin, orystrobin, dimoxystrobin, pyraclostrobin, fluoxastrobin, enestroburin, piraoxystrobin and pyrametostrobin;
[0047] oxazolidinone compounds such as famoxadone;
[0048] thiazolecarboxamide compounds such as etaboxam; [0049] valinamide compounds such as iprovalicarb and bentiavalicarb-isopropyl;
[0050] acylamino acid compounds such as methyl N (isopropyl-xicarbonyl) -L-valyl- (3RS) -3- (4-chlorophenyl) -3-alaninate (valiphenalate);
[0051] imidazolinone compounds such as fenamidone;
[0052] hydroxyanilide compounds such as fenexamide;
[0053] benzenesulfonamide compounds such as flussulfamiPetition 870180062559, of 07/20/2018, p. 14/32
10/19 da;
[0054] oxime ether compounds such as cyflufenamide;
[0055] anthraquinone compounds;
[0056] crotonic acid compounds;
[0057] antibiotic compounds such as validamycin, casugamycin and polyoxins;
[0058] guanidine compounds such as iminoctadine and dodine; [0059] quinoline compounds such as tebufloquine;
[0060] thiazolidine compounds such as flutianyl;
[0061] sulfur compounds such as sulfur;
[0062] and other compounds such as pyribencarb, isoprothiolane, piroquilone, diclomezina, quinoxifene, propamocarb hydrochloride, chloropicrine, dazomet, metam-sodium, metrafenone, UBF-307, diclocimeta, proquinazide, amisulbromide (other name: amibromdol) fluopicolide, carpropamide, meptildinocape, N - [(3 ', 4'-dichloro1,1-dimethyl) phenacyl] -3-trifluorome-til-2-pyridinecarboxamide, N - [(3', 4'dichloro-1,1- dimethyl) phenacyl] -3-methyl-2-thiophe-nocarboxamide, N - [(3 ', 4'dichloro-1,1-dimethyl) phenacyl-1-methyl-3-trifluoromethyl-4-pyrazolcarboxamide, N - [[ 2'-methyl-4 ^, - (2-propyloxy) -1,1-dimethyl] phenacyl] -3-trifluoro-methyl-2pyridinecarboxamide, N - [[2 ^, -methyl-4 ^, - (2-propyloxy) -1 , 1-dimethyl] phenacyl] -3methyl-2-thiophenecarboxamide, N - [[2'-methyl-4 ^, - (2-propyloxy) -1,1 dimethyl] phenacyl] -1-methyl-3-trifluoromethyl-4- pyrazolcarboxamide, N - [[4 '- (2propyloxy) -1,1-dimethyl] fe-nacyl] -3-trifluoromethyl-2-pyridinecarboxamide, N [[4 ^, - (2-propyloxy) -1,1-dimethyl] fe-nacil] -3-methyl-2-thiophenecarboxamide, N [[4 ^, - (2- propyloxy) -1,1-dimethyl] phenacyl] -1-methyl-3-trifluoromethyl-4 pyrazolcarboxamide, N - [[2 ^, -methyl-4 ^, - (2-pentyloxy) -1,1-dimethyl] phenacyl] -3trifluoromethyl -2-pyridinecarboxamide, N - [[4 '- (2-pentyloxy) -1,1dimethyl] phenacyl] -3-trifluoromethyl-2-pyridinecarboxamide, ferimzone, spiroxamine, S-2200, ZF-9646, BCM-061, BCM -062, S-8606, DKF-1001, MF-1001, MF-1002, NC-223, NK-1001, SB-4303 and BAF-1107.
Petition 870180062559, of 07/20/2018, p. 15/32
11/19 [0063] The active ingredient compounds of insect pest control agents, such as the insecticide, miticide, nematicide and soil insect pesticide in the agricultural chemicals mentioned above, include, for example, ( by common names, some of them still in the order stage or test codes of the Japan Plant Protection Association (Japan Plant Protection Association)):
[0064] Organic phosphate compounds, such as profenofos, dichlorvos, fenamiphos, fenitrothione, EPN, diazinone, chlorpyrifos, chlorpyrifosmethyl, acephate, protiofos, phosphiazate, cadusaphos, disulfotone, isoxationa, isofenfos, etion, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl, dimethyl. sulprofos, thiometone, vamidothione, piraclofos, pyridafentiona, pirimifosmetil, propafos, fosalona, formotiona, malationa, tetrachlorovinfos, chlorofenovinfos, cyanofos, trichlorofone, metidathione, fentoate, ESP, azinfosmetil, f metho, f metho, fhe monocrotophos, metamidofos, imiciafos, paration-methyl, terbufos, phosphamidone, phosmet and phorate;
[0065] carbamate compounds, such as carbaryl, propoxur, aldicarb, carbofuran, thiodicarb, methomyl, oxamil, ethiofencarb, pirimicarb, phenobucarb, carbosulfan, benfuracarb, bendiocarb, furatiocarb, isoprocarb, metolcarb, xylcarb, xylcarb, xylcarb, xylcarb, xylcarb, xylcarb, xylcarb;
[0066] nereistoxin derivatives, such as cartap, thiocyclam, bensultap and thiossultap-sodium;
[0067] organic chloride compounds, such as dicofol, tetradifone, endosulfan, dienochlor and dieldrin;
[0068] organic metal compounds, such as fenbutatin oxide and cyiexatin;
[0069] pyrethroid compounds, such as fenvalerate, permethrin, cypermethrin, deltamethrin, cyhalothrin, teflutrin, etofenprox, flufenprox, cyfluthrin, fenpropatrin, flucitrinate, fluvalinate, cycloprotine, lambdaPetição 870180062559, pág. 16/32
12/19 cyhalothrin, pyrethrins, sphenolvalerate, tetramethrin, resmethrin, protrifenbute, bifentrin, zeta-cypermethrin, acrinatrine, alpha-cypermethrin, allethrin, gamma-cyhalothrin, teta-cypermethrin, tau-fluvalin, beta-methyrethine, beta-methyrethine, beta-methatrine, ketamine -ciflutrin, metoflutrin, phenothrin and flumethrin;
[0070] benzoylurea compounds, such as diflubenzurone, chlorofluazurone, teflubenzurone, flufenoxurone, triflumurone, hexaflumurone, lufenurone, novalurone, noviflumurone, bistriflurone and fluazurone;
[0071] juvenile hormone-like compounds, such as methoprene, pyriproxyphene, phenoxycarb and diophenolan;
[0072] pyridazinone compounds, such as pyridaben;
[0073] pyrazole compounds, such as fenpyroximate, fipronil, tebufenpirade, etiprol, tolfenpirad, acetoprol, pirafluprol and pyriprol;
[0074] neonicotinoids, such as imidacloprid, nitenpiram, acetamipride, thiacloprid, thiamethoxam, clothianidin, nidinotefuran, dinotefuran and nitiazine;
[0075] hydrazine compounds, such as tebufenozide, methoxyfenozide, chromafenozide and halofenozide;
[0076] pyridine compounds, such as flonicamide;
[0077] tetronic acid compounds, such as spirodiclofen;
[0078] strobilurin compounds, such as fluacripyrim;
[0079] pyrimidinamine compounds, such as flufenerin;
[0080] dinitro compounds;
[0081] organic sulfur compounds;
[0082] urea compounds;
[0083] triazine compounds;
[0084] hydrazone compounds;
[0085] other compounds such as buprofezin, hexitiazox, amitraz, chlorodimeform, silafluofen, triazamate, pimetrozine, pyrimidifene, chlorophenapyr, indoxacarb, acequinocil, ethoxazole, cyromazine, 1,3
Petition 870180062559, of 07/20/2018, p. 17/32
13/19 dichloropropene, diafentiurone, benclothiaz, biphenazate, spiromesifene, spirotetramate, propargite, clofentezine, metaflumizone, flubendiamide, cyflumetofen, chlorantraniliprol, cyienopyrae, pyrifluquinone, hydrochloride, sulfamide, hydroquinone, , ryanodine, pyridalil and verbutine. In addition, it can be mixed with or used in combination with agricultural microbial chemicals, such as Bacillus thuringiensis aizawai, Bacillus thuringiensis kurstaki, Bacillus thuringiensis israelensis, Bacillus thuringiensis japonensis, Bacillus thuringiensis tenebrionis or insecticidal crystal proteins produced by Bacillus thensiensis, produced by Bacillus from insects, etomopathogenic fungi, and nematophage fungi: antibiotics or semi-synthetic antibiotics, such as avermectin, emamectin benzoate, milbemectin, milbemycin, spinosad, ivermectin, lepimectin, DE-175, abamectin, emamectin and spinam; natural products, such as azadiractin, and rotenone; and repellents, such as deet.
[0086] In the fungicidal composition of the present invention, the appropriate blend weight ratio of component (a) to component (b) is preferably 1: 5000 to 5000: 1, more preferably 1: 1000 to 1000: 1, particularly preferable from 1: 500 to 500: 1.
[0087] A method for controlling plant diseases, which comprises applying the fungicidal composition of the present invention to agricultural and horticultural plants, is also included in the present invention. The concentration of the fungicidal composition of the present invention cannot be defined in general, as it varies depending on the plants of the culture to be treated, the method of application, the type of formulation, the dose, etc. However, it is adjusted in such a way that the concentration of component (a) is preferably 200 to 0.05 ppm, more preferably 100 to 0.1 ppm, and the concentration of component (b) is preferably 1,000 to 1 ppm, more I preferred
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14/19 from 1,000 to 10 ppm, particularly preferably from 500 to 20 ppm, in the case of leaf treatment. In the case of soil treatment, the concentration is adjusted in such a way that the concentration of component (a) is preferably 200 to 10 g / ha, more preferably 100 to 20 g / ha and the concentration of component (b) is preferably from 1,000 to 50 g / ha, more preferably from 500 to 40 g / ha.
[0088] The formulation containing the fungicidal composition of the present invention or a diluted product thereof can be applied by an application method that is commonly used, such as spraying (such as spraying, jetting, vaporizing, atomizing, spraying or spreading grains) , or dispersing in water), application to the ground (such as mixing or soaking) or surface application (such as coating, spraying or covering). In addition, it can also be applied by the so-called ultra low volume application method. In this method, the formulation can be made up of 100% of the active ingredients.
Examples [0089] Now, Test Examples of the present invention will be described, but it should be understood that the present invention is in no way restricted to this.
TEST EXAMPLE 1: TEST ON PREVENTIVE EFFECT AGAINST POROUS WHEAT MILK [0090] Wheat (cultivar: Norin-61) was grown in a plastic pot having a diameter of 7.5 cm, and when it reaches stage 1, 5 of the sheet, a chemical solution having the test compound adjusted to a prescribed concentration, was applied by a spray gun in an amount of 5 ml / seed. After the dry chemical solution, Erysiphe qraminis conidia were sprayed and inoculated and kept in a constant temperature chamber at 20 ° C. From 6 to 8 days after inoculation, the sporulation area was investigated, and the value
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15/19 control was determined according to the following formula, and the results are shown in Tables 1 to 7. The sporulation area in the untreated plane was determined in the same way as for the treated plane except that the water was applied with a spray gun instead of chemical solution.
[0091] Value control = (1-a / b) x 100 a: sporulation area the treated plane b: sporulation area in the untreated plane [0092] Based on the obtained value control, an expected value (value control ) was calculated using the Colb formula. The values expected by the Colby formula are also shown in parentheses () in Tables 1 to 7.
[0093] When the experimental value is greater than the expected value, the fungicidal composition of the present invention has a synergistic effect against porous downy mildew.
Table 1
Bixafen concentration Concentration of component (a) 0.5 ppm 0.25 ppm 0.125 ppm 0 ppm 500 ppm 97.5 (75) 95 (65) 95 (65) 50 250 ppm 97.5 (50) 90 (30) 50 (30) 0 0 ppm 50 30 30
Table 2
Isopyrazam concentration Concentration of component (a) 0.5 ppm 0.25 ppm 0.125 ppm 0 ppm 31 ppm 100 (95) 97.5 (93) 97.5 (93) 90 16 ppm 97.5 (75) 95 (65) 92.5 (65) 50 0 ppm 50 30 30
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16/19
Table 3
Fluopyram concentration Concentration of component (a) 0.5 ppm 0.25 ppm 0.125 ppm 0 ppm 31 ppm 100 (85) 100 (79) 97.5 (79) 70 16 ppm 100 (70) 92.5 (58) 72.5 (58) 40 0 ppm 50 30 30
Table 4
Ametoctradine concentration Concentration of component (a) 0.5 ppm 0.25 ppm 0.125 ppm 0 ppm 400 ppm 100 (57.5) 100 (40.5) 95 (40.5) 15 200 ppm 100 (50) 95 (30) 90 (30) 0 0 ppm 50 30 30
Table 5
Silkxane concentration component (a) Concentration of 0.5 ppm 0.125 ppm 0 ppm 12.5 ppm 92.5 (58) 60 (30) 30 6.3 ppm 92.5 (40) 60 (0) 0 0 ppm 40 0
Table 6
Concentration of phenpyrazamine Concentration of component (a) 0.5 ppm 0.125 ppm 0 ppm 250 ppm 70 (40) 30 (0) 0 63 ppm 70 (40) 30 (0) 0 0 ppm 40 0
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17/19
Table 7
Flowpyroxade concentration Concentration of component (a) 0.5 ppm 0.125 ppm 0 ppm 50 ppm 95 (70) 82.5 (50) 50 6.3 ppm 90 (58) 70 (30) 30 0 ppm 40 0
TEST EXAMPLE 2: TESTING THE PREVENTIVE EFFECT GRAY MOFO ON WHITE BEANS [0094] White beans (cultivar: Taishokintoki) was grown in a plastic pot having a diameter of 12 cm, and when it reached 3 to 4-leaf stages , a chemical solution having each test compound adjusted to a prescribed concentration, was applied by a spray gun in an amount of 10 ml / seed. After the chemical solution was dry, a conidial suspension of Botrytis cinerea was stained on a paper disk having a diameter of 8 mm for inoculation of the implant and kept in a constant temperature chamber at 20 ° C. Upon expiration of 3 days from inoculation, the lesion area was investigated, and the value control was determined according to the following formula, and the results are shown in Table 8. The lesion area in the untreated plane was determined in the same way as for the treated plane except that water was applied by a spray gun instead of chemical solution.
[0095] Value control = (1-a / b) x 100 a: area of injury in the treated plane b: area of injury in the untreated plane [0096] Based on the value control obtained, an expected value (value control ) was calculated using the Colby formula. The values are
Petition 870180062559, of 07/20/2018, p. 22/32
18/19 per the Colby formula are also shown in parentheses () in Table 8.
[0097] When the experimental value is greater than the expected value, the fungicidal composition of the present invention has a synergistic effect against the gray mold of white beans.
Table 8
Penflufen concentration Concentration of component (a) 400 ppm 200 ppm 0 ppm 100 ppm 95 (50) 92.5 (50) 50 50 ppm 70 (40) 70 (40) 40 0 ppm 0 0
[0098] Now, Formulation Examples of the present invention will be described below. However, the proportion of the mixture, the type of formulation or the like in the present invention are in no way restricted to the following Examples.
FORMULATION OF EXAMPLE 1
(The) Kaolin 78 parts by weight (B) Condensed acid sodium salt β-naphthalenesulfonic with formalin 2 parts by weight (ç) Polyoxyethylene alkylaryl sulfate 5 parts by weight (d) Hydrated amorphous silicone dioxide 15 parts by weight
[0099] A mixture of the above components, component (a) and component (b) are mixed together in an 8: 1: 1 weight ratio to obtain a moisturizing powder.
FORMULATION EXAMPLE 2 (a) Component (a) 0.5 part by weight (b) Component (b) 0.5 part by weight
Petition 870180062559, of 07/20/2018, p. 23/32
19/19 (c) Bentonite 20 parts by weight (d) Kaolin 74 parts by weight (e) Sodium lignin sulfonate 5 parts by weight [00100] An appropriate amount of water for granulation is added to the above components and mixed, and the mixture and is granulated to obtain granules.
FORMULATION EXAMPLE 3 (a) Component (a) (b) Component (b) parts by weight parts by weight (c) Talc parts by weight [00101] The above components are uniformly mixed to obtain a powder.
[00102] The full description of Japanese Patent Application No.
2011-151807 filed on July 8, 2011 including descriptive report, claims, drawings and summary is incorporated here by reference in its complete form.
Petition 870180062559, of 07/20/2018, p. 24/32

权利要求:
Claims (2)
[1]
REQUIREMENTS
1. Fungicidal composition, characterized by the fact that it comprises, as active ingredients, (a) 3- (2,3,4-trimethoxy-6methylbenzoyl) -5-chloro-2-methoxy-4-methylpyridine or its salts and (b ) bixafen, where the ratio of mixed weight from (a) to (b) is 5: 1, 4: 1, 2: 1, 1: 1, 1: 2, 2: 5, 1: 4, 1: 5 , 1:10, 1: 500, 1: 1000 or 1: 2000.
[2]
2. Method for controlling plant diseases, characterized in that it comprises applying a fungicidal composition, as defined in claim 1, to plants.

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法律状态:
2016-09-20| B06F| Objections, documents and/or translations needed after an examination request according art. 34 industrial property law|

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2018-04-24| B07A| Technical examination (opinion): publication of technical examination (opinion)|

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2019-01-08| B06A| Notification to applicant to reply to the report for non-patentability or inadequacy of the application according art. 36 industrial patent law|

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2019-07-09| B09A| Decision: intention to grant|

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2019-08-27| B16A| Patent or certificate of addition of invention granted|Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/06/2012, OBSERVADAS AS CONDICOES LEGAIS. (CO) 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/06/2012, OBSERVADAS AS CONDICOES LEGAIS |

优先权:

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申请号 | 申请日 | 专利标题

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JP2011151807|2011-07-08|

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PCT/JP2012/065925|WO2013008604A1|2011-07-08|2012-06-15|Fungicidal composition and method for controlling plant diseases|

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